Antihistamine drugs, such as Benadryl, Allegra, and Claritin, might stave off the coronavirus, according to a recent study published by the American Society of Microbiology Journals.
The study uncovered that a histamine receptor known as HRH1 can serve as an alternative entry point for the SARS-CoV-2 virus, directly interacting with its spike protein. This interaction not only facilitates viral entry but also enhances it in conjunction with the human angiotensin-converting enzyme 2 (hACE2), another receptor crucial for the virus.
By blocking HRH1, antihistamine drugs disrupt this interaction, effectively preventing viral entry. Laboratory tests showed that these drugs inhibited infection from various SARS-CoV-2 variants with a notable effectiveness.
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